“Give Smiles, Not Gifts”: Chula’s Original Short Film Captures Graduates’ Perspective on Gifts for Graduation Day

The Office of Student Affairs and Chulalongkorn University Communication Center have collaborated to produce the original short film “Give Smiles, Not Gifts,” reflecting on what graduates would like for their graduation day under the concept “Heart is the best gift.” The film was produced to congratulate all of the 2022 graduates and promote the campaign to reduce the practice of giving extravagant gifts, such as flowers and balloons, to minimize waste generation, support environmental friendliness, and transform graduation celebrations into occasions for sharing smiles rather than receiving gifts.

The short film “Give Smiles, Not Gifts” was produced by Chatchai Kunponpitak and directed by Chatchai Prasertmak.  Both the director and production team have previously created short films about the Chula graduation ceremony. “Life of Kwan” and “The Gift,” produced by them for Chula’s graduation, won awards from the WINA World Independent Advertising Awards, a world-class advertising film competition, in 2020 and 2019, respectively.

To watch the short film, “Give Smiles, Not Gifts”, click here: https://youtu.be/G6IRt6GtpN0?si=ctJizaKVhkNlchRD

Enjoy Your Temple Tour, Learn More with the “Insight Wat Pho” Application, A Social Innovation from Chula Architecture

“Insight Wat Pho” an innovation for society by a Chula Architecture lecturer is a companion application that helps visitors plan and make the most out of their visit to Wat Pho. With helpful info on how to get there and points of interest, to fun features, such as AR (augmented reality) floor plan of Wat Pho and “Yak Wat Pho” hunt game to find the Wat Pho’s Giants, the app can help visitors have a trip that is more meaningful and enjoyable.

Many popular period Thai series have created a trend of both Thai and foreign tourists flocking to ancient sites, such as “Wat Phra Chetuphon Wimon Mangkhalaram Rajwaramahawihan” or “Wat Pho”, one of the most popular tourist attractions in Bangkok and Thailand, attracting around 10,000 – 15,000 tourists each day!

Although the trend of dressing in Thai costumes and taking pictures in different archaeological sites is a form of soft power that helps boost the local economy, there are environmental impacts that should also be managed.

“Wat Pho is a place of worship that we must respect and an archaeological site that must be preserved, but we can see tourists climbing the structures without realizing their priceless value and the fact that these structures have existed for over a hundred years. Should there be any damage it is most difficult to repair,” said Dr. Wilasinee Suksawang, a lecturer at the Department of Landscape Architecture, Faculty of Architecture, Chulalongkorn University.

Inappropriate behavior that has been creating problems for this important tourist attraction pushed Dr. Wilasinee to initiate the social innovation project “Insight Wat Pho” to mitigate the impacts, which would be too late if not managed today. As an architecture professor who has been working tirelessly with the local community, professor Wilasinee believes that effective solutions to environmental problems should tackle their root cause by promoting environmental education.

“Nowadays, rather than solving environmental problems at the root cause, we often just treat the symptoms of those problems. For example, when the water is polluted, one develops many water treatment techniques. Ultimately, such an approach is unsustainable,” said Dr. Wilasinee.

“If people are knowledgeable about the environment, they will know what causes the problems and how to solve them. How can we, as part of the environment, contribute to mitigating, reducing, and not creating problems? Will this be a more sustainable approach than treating the problems at the results?”, explained the professor on the importance of applying the concept of Environmental Education and Environmental Ethics in solving the problems of Wat Pho.

Wat Pho, a tourist attraction, and educational destination with high potential. There are numerous historical sites in Thailand, and many of them are also facing the effects of tourism, but Dr. Wilasinee chose to start with Wat Pho as it is a high-potential tourist attraction.

Wat Pho is a historically significant Royal Temple. There are sacred icons that people worship. The architecture is distinctive, beautiful, and most importantly, “Wat Pho is regarded as the first university in Thailand. There are many recipes for medicine, and Thai massage references that are inscribed on stone tablets in the temple.”

“There is a considerable body of knowledge about Wat Pho, but it is accumulated in library books that nobody reads. So, I have been thinking about how we can make the knowledge accessible to the general public and make their visit more interesting. Instead of just visiting the temple and leaving, how do I get the visitors to prolong their stay in the temple with more fun and knowledge?” explained Dr. Wilasinee about the development of the “Insight Wat Pho” application to educate the general public about Wat Pho, so that they realize the value of the place, and lead to co-preservation and environmental impact reduction.

7 features to try! Take a tour of Wat Pho with deep insight
The “Insight Wat Pho” application did not start from scratch. Academia and experts have already been researching and collecting elaborate data about Wat Pho, including 3D models. “It would be a pity if all the research we have done, and the models would be kept on a computer when people should benefit from it.”

Therefore, Dr. Wilasinee and the Chulalongkorn Architecture research team have collaborated with several agencies, namely Wat Pho, and the National Innovation Agency (NIA), to curate interesting and useful information to provide Wat Pho visitors with the best experience.

“Insight Wat Pho” consists of 3 major features that provide basic information, and 4 more fun features that will educate visitors while they have fun:

Plan Your Visit
Dr. Wilasinee said, “When we travel to a certain place, we need a plan — how to get there, when it opens, how to buy tickets. These are the first things one should know. Therefore, anyone who is planning to visit Wat Pho can find this information from the Insight Wat Pho application. I can guarantee that the information is complete. There is no way you can get lost.”

Visitor Map
The layout of Wat Pho is quite complex and may make it difficult to walk around, and you may miss important spots, so having a map handy will make it easier.

“Although Wat Pho already has maps displayed at different points, in reality, we couldn’t find a map when we needed one, so having a map at our fingertip will give us peace of mind,” said Dr. Wilasinee.

Wat Pho in History
This feature shows the significant development of Wat Pho in three periods: King Rama I, King Rama III, and the present day. It is displayed as a 3D layout to portray what Wat Pho looks like in each era and how it has changed today.

Wat Pho from the Sky
This feature will take you to see Wat Pho from every corner by looking for the markers placed on the ground inside Wat Pho. When the marker is scanned, an AR diagram of Wat Pho will be displayed.

“We chose AR for this app because it is useful and fun for people. You can rotate, zoom in and out, and get a better understanding of the layout, details of the architecture, and the placement of the buildings.”

Explore
This feature will take you to explore the things that are not to be missed in Wat Pho, especially the important architecture and Buddha statues that we can not only see with our eyes but also scan and hear sounds and descriptions that will help us better understand the story of what is in front of us.

In addition, another not-to-be-missed fun is the “Poetry Quizzes” based on the Wat Pho stone inscriptions found on the pillars of the balcony.

“The Epigraphic Archives of Wat Pho are UNESCO-registered artifacts, some of which are in the form of puzzles. When we look at the inscription through the app, it will appear as an AR image, and there will be an audio poetry reading of that inscription for us. This function will allow us to complete the tour around the balcony without even knowing it.”

Freeze-Frames
In the app, there are pictures of different angles in Wat Pho from about 100 years ago. Users will have to find those spots today and compare how Wat Pho has changed. It is another feature that will take us to walk all over Wat Pho, and it’s great for photography enthusiasts.

Yak Wat Pho (Wat Pho’s Giants)
“I believe many people do not know what a Wat Pho’s Giants look like and where they are,” said Dr. Wilasinee, referring to the origins of the highlight feature like “I am a Yak Wat Pho.”

“When we are in Wat Pho, we will see so many statues of giants everywhere. So, which one is the real Wat Pho Giant? This feature provides a map indicating the coordinates of the giants. When we walk to the giants, the app will explain their details. “The map will take us around the temple to see various giants. Some giants may be in a form that we would not expect at all. Therefore, it is challenging to find all the giants and the hunt will attract us to spend a lot longer time in the temple.

The future of Insight Wat Pho
Dr. Wilasinee said that there are still many interesting stories about Wat Pho. The development team will continue to add information to the app. But the more challenging matter is not about Wat Pho’s information, but the business model that will allow the “Insight Wat Pho” app to thrive.

“Insight Wat Pho” is a free app. We do not want learning to cost money. So, to survive, we must rely on a business model. We are thinking of building Insight Wat Pho as a platform to support tourism and activities in Wat Pho, such as booking tickets to special events such as watercolor painting in Wat Pho, Wat Pho night tour, or reservation of special-edition souvenirs, and so on — which can only be done exclusively through the app. This also includes reservation of certified tour guides who are knowledgeable about Wat Pho. All of this will be included in the plan, said Dr. Wilasinee.

Insight Wat Pho – Not Just a Travel App
The “Insight Wat Pho” application is not just intended for users to have fun and gain knowledge, but Dr. Wilasinee is convinced that this innovation will make an impact on society in terms of culture, environment, and economy.

“We would like to see a behavior change in Wat Pho visitors from just sightseeing to exploring around to learn the history and culture of Thailand, and not missing the interesting spots. When tourists can spend a longer time in this place, they will support local shops and community stores when they are tired or hungry. This will not only bring a positive impact to tourism as a whole but also help draw monetary contributions into the communities,” said Dr. Wilasinee.

In this regard, Dr. Wilasinee also mentioned plans to expand the project to other historically significant places. The next temple in mind is “Wat Arun Ratchawaram Ratchawaramahaviharn (The Temple of Dawn)”, which is considered the “son temple” of Wat Pho (Wat Pho is the temple of King Rama I, while Wat Arun is the temple dedicated to King Rama II). Wat Arun has also been affected by the popularity among tourists dressed in Thai costumes looking for photo corners as backdrops in historical places as well.

Those interested in trying the Insight Wat Pho app can download it for free on the App Store and Google Play, or follow the app on Facebook: Insight Wat Pho.

Chulalongkorn’s Faculty of Architecture signs MOU with Taiwan Design Research Institute (TDRI) to develop designs for future diversity

Chulalongkorn University’s Faculty of Architecture showcased its students’ theses and dissertation works, as well as the faculty’s curriculum at YODEX 2023 held from May 19 – 23, 2023, at Nangang Exhibition Hall, Taipei, Taiwan. Asst. Prof. Sarayut Supsook, Dean of the Faculty of Architecture, Chulalongkorn University, also signed an MOU for academic collaboration with Mr. Chi-Yi Chang, Taiwan Design Research Institute (TDRI) President, with Mr. Taweekiat Janeprajak, Executive Director of Thailand Trade and Economic Office (Taipei), and Mr. Simon Wang, President & CEO of Taiwan External Trade Development Council, witnessing the event. The Dean also visited the office of TDRI for a discussion on possible joint efforts to promote academic activities.

The exhibition marks the second collaboration between the Faculty of Architecture, Chulalongkorn University, and Taiwan Design Research Institute (TDRI). The first activity, held on May 8, 2023, at the Faculty of Architecture Library, was a talk by Mr. Oliver Lin, executive and representative of Taiwan Design Research Institute (TDRI), introducing the Ideathon 2023: WeWe Future international contest under the theme “Diversity & Inclusion in 2040.” The contest opened for applications from contestants all over the world from July 1, 2023, at 10:00 am to July 31, 2023, at 5:00 pm (GMT+8).

The event also featured a special lecture on “Space for Contemplation” by Ms. Sanitas Pradittasnee from Sanitas Studio, an alumnus of the Faculty of Architecture, Chulalongkorn University, who shared her ideas for mindful creation that draw inspiration from the environment and encourages the audience to imagine what might happen in the future.

For the full release and more images, please visit: https://www.chula.ac.th/en/news/128310/

Scratch where it itches

Chula Veterinary Science Lecturers have successfully developed a Serum Test Kit to Identify Canine Atopic Dermatitis (CAD) caused by dust mites. With a Gold Medal from the Swiss Innovation Contest, the test kit is guaranteed to help identify the allergens with greater precision to ensure correct treatment.

Atopic dermatitis is one of the most common allergies in dogs, with prominent symptoms such as itching, erythema, and severe swelling. In severe cases, there can be symptoms of bronchospasm, coughing, and sneezing like people with allergies.

Itching and erythema in dogs are not to be overlooked. Dog owners should pay attention and take their pets to be examined and receive appropriate and spot-on care, which can only be done if the cause or culprit of the skin allergy can be identified.

Screening for skin allergy in dogs is quite limited, complex, time-consuming, and very costly. Associate Professor Dr. Nuvee Prapasarakul, Department of Microbiology, Faculty of Veterinary Science, Chulalongkorn University, and a team of researchers, consisting of Dr. Nathrada Khanthawee, Associate Professor Dr. Nitat Sookrung, Miss Nawannaporn Lim, and Assistant Professor Dr. Wandee Sirichokchatchawan, therefore, invented and developed “a Serum Test Kit to Identify Canine Atopic Dermatitis (CAD) caused by dust mite using Immunoglobulin G1 (G subclass one) to help veterinarians identify the cause of allergy in dogs more quickly and easily.

“This test kit can be used continuously from the start of allergy testing, during symptom monitoring until the end of treatment without the dog getting hurt, and it can also be cost-effective,” said Assoc. Prof. Dr. Nuvee about the hallmark of this innovation, which won the gold medal at the 48th International Exhibition of Inventions 2023 held recently in Geneva, the Swiss Confederation.

Getting to Know Canine Atopic Dermatitis (CAD) and Its Causes
Canine Atopic Dermatitis (CAD) is one of the most common forms of skin allergy in dogs, caused by abnormal immune responses to environmental agents such as airborne chemicals, dust, mold, mites, and food.

“Healthy and unhealthy dogs all have the potential to develop this disease. The incidence of skin diseases varies depending on the nature of each dog. Some dog breeds may have frequent skin diseases and severe symptoms, while others may have only minor symptoms and some may not have skin diseases at all,” said Associate Professor Dr. Nuvee.

CAD can be the result of a variety of factors, including:

1. Genetics: Some breeds of dogs are at higher risk than others for AD, including Vizla, Bassett Hound, Yorkshire Terrier, Shih Tzu, Beagle, Bulldog, and Cocker Spaniel. Dogs with weakened immunity or stress are also more prone to skin diseases.

2. Age: Skin allergies in dogs usually start showing symptoms between the ages of 6 months and 3 years old, but symptoms can also occur at any age.

3. Environmental conditions such as dust, dust mites, and high humidity increase the likelihood of developing fungus on the dog’s skin, causing skin irritation and allergies. Cold and dry weather can also dry the dog’s skin, aggravating skin allergies. In hot weather, dogs have more skin problems, which can be a risk factor to develop further skin allergies.

4. Chemicals: Exposure to certain chemicals can be a trigger for skin allergies, especially those used in dog health care products such as soap, shampoo, cream, or some coating substance can all trigger an onset of skin allergy in dogs that are sensitive to these chemicals.

5. Food: Protein from food contributes to around 10-15 percent of skin allergy cases.

However, according to Assoc. Prof. Dr. Nuvee, most skin allergies in dogs are caused by allergens in the environment such as dust mites, pollen, mold, and other substances that dogs come into contact with, especially dust mites which are important factors in triggering allergies.

 

Atopic Dermatitis Caused by Dust Mites
Dogs with skin allergies from dust mites itch and scratch on the affected skin such as around the ears, abdomen, legs, and under the body. They are plagued with skin eczema, erythema, scarring, or scabby skin on sensitive areas that smell like fermented yeast.

In some cases, the dogs suffering from CAD may experience swelling, redness, and pus in the affected areas. They may have increased hair loss and ulcers caused by scratching or incorrect skin treatment.

Although the majority of canine skin allergies are mainly caused by dust mites, there may be other causes, such as dietary, that may trigger similar symptoms.

How important is allergen identification?
Assoc. Prof. Dr. Nuvee said that identifying allergens is very important to help reduce or avoid them, as well as to help plan for the right treatment, such as the correct administration of anti-allergic medications to reduce the risk of dogs receiving unnecessary or inappropriate treatment.

“Allergies and how to treat them are specific and dependent on each dog and their living environment. A veterinarian specializing in allergies can provide additional counsel on proper handling and allergy prevention for dogs, as well as how to boost their immunity to fight the allergies which helps to somewhat relieve the symptoms. A healthy immunity may strengthen a dog’s tissues and immune system to reduce an abnormal response to something it is allergic to.”

Assoc. Prof. Dr. Nuvee also added that dogs may be allergic to the things being watched for the rest of their lives, or they may develop allergic reactions to something new as well.

Allergen Screening Test Before Planning a Treatment
Allergies in dogs can occur when the dog is 6 months of age or older. Assoc. Prof. Dr. Nuvee recommends that dog owners regularly observe skin symptoms similar to those of skin allergies, such as itching, redness, dampness, thick skin, or dandruff scabs. Should these symptoms occur, you should consult veterinarians specializing in skin diseases or allergies.

“Owners should take note of the dog’s symptoms and response to the environment as information for veterinarians to diagnose and provide appropriate guidance in the management of diseases that may require long-term follow-up treatment to control skin symptoms and disorders.”

Identifying the specific allergens is important in treatment planning. According to Assoc. Prof. Dr. Nuvee, there are currently two test methods:

1. Intradermal skin test is a test under the skin to diagnose airborne allergies. The veterinarian will inject the test substance into the skin layer of the dog and observe the symptoms for some time before evaluating the results according to the dog’s response. The process takes about 1-2 hours.

“There are limitations to this method. Before the dog is tested, all the medications, i.e., anti-inflammatory, anti-itching, immunosuppressant have to be stopped. So, there are risks of the symptoms becoming acute. In addition, this method requires anesthesia, and it is expensive.”

2. Allergen-specific IgE serology testing is a method of detecting airborne allergy symptoms in dogs by measuring the level of Immunoglobulin E (IgE) antibodies produced by the body causing allergic reactions to possible allergens. This test is done on samples of the dog’s blood.

“This method is quite convenient, but not many veterinary laboratories in Thailand provide this service which means they have to send blood samples to foreign laboratories, making it costly, and time consuming. Most importantly, this method requires a substantial amount of blood for the test.”

Scratch where it itches! Innovative Allergen Screening Test Kit with High Precision
Based on the limitations of the two allergen screening tests, Assoc. Prof. Dr. Nuvee, therefore, developed the Serum Test Kit to Identify Canine Atopic Dermatitis (CAD) caused by dust mites using Immunoglobulin G1 (IgG Subclass 1) using a laboratory method called ELISA (Enzyme-Linked Immunosorbent Assay).

Assoc. Prof. Dr. Nuvee explained that “Immunoglobulin G subclass One” is one of the four subclasses of Immunoglobulin G in the immune systems of humans and animals, whose main function is to protect the body from allergies and pathogens. Assessing the level and proportion of each class of Immunoglobulin G can help to diagnose and monitor the immune response to various substances or infections in various forms in the body.

“The research team found that the “immunoglobulin G subclass1” is the primary class of “immunoglobulin G” with a high response rate to allergens in dogs with CAD.”

During the course of the research, Assoc. Prof. Dr. Nuvee tested this test kit on 200 dogs at participating veterinary hospitals throughout Bangkok with satisfactory results, comparable to the effectiveness of the original two methods.

“While we don’t have the best test kit yet, this is an easily accessible method for veterinarians, and it can be used continuously from diagnosis, monitoring, and end-of-treatment without hurting the dogs while being cost-effective,” said Assoc. Prof. Dr. Nuvee. Articles about this innovative serum test kit to identify dust mite allergy in dogs have been published in three Q1 international journals.

Guidelines for the Care and Treatment of CAD
Care and treatment of skin allergies in dogs is a complex process and should be supervised by a veterinarian to ensure proper care for the dogs in each household. Assoc. Prof. Dr. Nuvee summarizes the guidelines for care as follows:

1. Remove allergens – For example, if the dog is allergic to dust, pollen, or dietary protein, the food must be reduced or removed from the dog’s environment as much as possible to reduce exposure and immune response.

2. Feed the dog proper food that does not contain ingredients that can induce dog allergies to reduce the immune response.

3. Use immune-boosting substances such as vitamins and other supplements

“Boosting immunity can help reduce some of the allergies in dogs. A strong immunity can potentially strengthen the dog’s tissues and immune system to reduce abnormal responses to allergens.”

Use medications and medical treatment. In case of severe allergies, the veterinarian may recommend the use of related medications such as steroids, anti-allergy drugs, antifungal drugs, antibiotics, and hair tonics to effectively control allergies. The owner is recommended to administer medication regularly.
Minimize anything that may trigger an allergic reaction, such as washing bed linen, clothing, and household appliances thoroughly. Use mild shampoos to wash the dogs, and focus on general hygiene with proper exercise, proper feeding, and appropriate climate control.
Currently, the Serum Test Kit to Identify Canine Atopic Dermatitis (CAD) caused by dust mites using Immunoglobulin G1 (G subclass one) has already been patented. In the future, Assoc. Prof. Dr. Nuvee intends to develop this innovation into a paper-based, ATK-like test kit for convenience and easy detection of the allergy in one go, while being able to identify other canine allergies in addition to dust mites, such as pollen, food protein allergies, etc.

Moreover, Assoc. Prof. Dr. Nuvee also plans to develop a vaccine, also known as Allergy Immunotherapy or Allergen-Specific Immunotherapy (ASI), as injections to treat allergies accurately!

For more information, contact the Research Department, Faculty of Veterinary Science, Chulalongkorn University, Tel. +66-2218-9440.

For the full release and more images, please visit: https://www.chula.ac.th/en/highlight/125823/

Learning Thai: A guide for foreigners interested in studying the local language in Thailand

Thailand has a lot of charms to indulge in, but one of the appeals one cannot deny is the “Thai language” which, in any shape or form, is so melodious and pleasing to the ear.

“Lately, we are seeing more and more people from many countries around the world become interested in learning the Thai language. With this booming interest comes the advent of many things: the digital world, the end of language barriers, easier travel, the export of goods and drama series, and various soft power trends,” said Assistant Professor Dr. Kiat Thepchuaysuk, Director of the Center for Thai as a Foreign Language (CTFL), Chulalongkorn University.

Whether you are studying for a career, doing business, learning to communicate with favorite stars, or even learning the language just for fun, most foreigners say the same thing: “The Thai language is hard.”

But for Dr. Kiat, a specialist in linguistics and teaching Thai language to foreigners, “Thai is easier to understand than you think, and can actually be a lot of fun if we know the basics, tricks, and tips.”

In this article, Dr. Kiat will give advice and easy-to-understand language tips for those who are thinking seriously about learning Thai. Native speakers will also learn fun facts about the language that will show that Thai is not as complicated as you think. It is actually a charming language that reflects the fun and creativity of the Thai people.

Mastering Thai Language Grammar: Key Rules and Concepts
Thai language of today is influenced by a combination of many languages such as Bali, Sanskrit, Khmer, Chinese, Javanese, Burmese, Malay, Persian, and some European languages such as Portuguese and English, etc. The vocabulary and grammar of Thai language, therefore, have certain traces of those languages as well. According to Dr. Kiat, a few grammatical points of Thai language that foreigners should know before starting their study to learn faster and understand the Thai language more easily are:

Arrangement of words in declarative sentences
Normally, when we learn different languages, we have to look at the basic sentence form of how the subject, verb, and object are arranged. Thai language uses the same structure as English or Chinese, i.e. subject > verb > object, for example, I eat rice. This is different from some languages which have the structure of subject > object > verb, such as Japanese or Korean, making it “I rice eat.”

Although two languages may share similar basic sentence structures, the grammar of both languages is not necessarily identical. This is only one way to easily understand a simple basic sentence in speech. Although Thai and Chinese speak in the same pattern of subject, verb, and object, Chinese language has a different structure of noun phrases from Thai language. Therefore, instead of saying “I eat two plates of rice,” a native Chinese speaker may misspeak and say “I eat two rice plates, for example.”

Therefore, if you want to speak Thai like a native speaker using more complex sentences, you need to learn more grammar.

“Many Thai language grammatical features are quite easy to understand and straightforward compared to many other languages because we have no tense, no verb conjugation, no complicated grammar rules. In Thai language, you just memorize the vocabulary and string the words together, and you’ll be able to communicate in Thai without difficulty,” Dr. Kiat explained.

Forming simple negative sentences and questions.
Now that you know how to write a simple sentence, if you want to use different forms of sentence, such as negative sentences, all you have to do is add the word “no (mai)” to the front of the verb, or for a question, add the word “mai (different tone)” to the end of the sentence. It’s very simple.

Describing a noun – put the noun first, then the adjective
Describing nouns in Thai language is different from some other languages. In other words, in Thai, we usually say the main noun first and then the descriptive or complementary words. Let’s look at the words “hot tea” in English, Japanese, Chinese, or Korean. The word “hot” is said first, then the main noun “tea”. Therefore, if a foreigner who speaks these languages come to learn the Thai language and does not understand this grammar, they can easily make mistakes in the word order.

In addition, there are many fascinating aspects of the Thai language that foreigners can learn about, including the writing system, grammar, pronunciation, sentences, consonants, vowels, and tones, which Thai people might not have thought about. Those interested can read the full article at https://www.chula.ac.th/en/highlight/123363/.

NSTDA, Chula Dentistry unveil toothpaste prototype to improve children’s oral health

The Assistive Technology and Medical Devices Research Center (A-MED), a division under the National Science and Technology Development Agency (NSTDA), Ministry of Higher Education, Science, Research and Innovation, together with the Faculty of Dentistry, Chulalongkorn University, have unveiled an innovative toothpaste prototype with nano-hydroxyapatite that helps to replenish minerals and strengthen tooth enamel.

The project aims to promote and develop oral health and dental care products to improve the quality of life and oral healthcare for Thai people, as well as address disparities among consumers. By fostering the development of dental advancements by Thai dentists and academics, the collaboration aims to strengthen Thailand’s medical sector and reduce dependence on imported resources. The press conference to showcase the toothpaste prototype took placed on May 30, 2023 at the Faculty Executive Committee meeting room, Vajwittayawat Building, Faculty of Dentistry, Chulalongkorn University.

Dr. Kitti Wongthavarawat, Head of the Health Innovation and Information Research Team, Assistive Technology and Medical Devices Research Center (A-MED), explained that when dental caries show up in children, it is the beginning of a series of long-term oral health issues. Presently, over 50% of Thai children currently suffer from tooth decay, and more than 60% of adults suffer from gingivitis due to limited access to adequate dental treatment. The nano-hydroxyapatite toothpaste prototype is the result of collaborative research, development, testing, design, and production of toothpaste products for the treatment of life-impeding oral health issues, such as early tooth decay, which usually happens because of lack of regular good oral health care.

Development of the nano-hydroxyapatite materials was jointly carried out by the research teams from A-MED, NSTDA, and the Faculty of Dentistry at Chulalongkorn University. This novel material was created via a mechanical chemical method and has a structure similar to human bones and teeth. Nano-hydroxyapatite can be used as a component in toothpaste due to its compatibility with human tissues and capability to promote tooth enamel remineralization. By focusing on nano-sized hydroxyapatite, Thai researchers can help reduce reliance on imports, improve access to domestically manufactured high-quality medical materials, and maintain international medical standards that align with BCG medical device policy objectives.

“The official launch of this prototype toothpaste marks another significant milestone in the two organizations’ successful partnership, as both collaborate to develop advanced preparation techniques for nano-hydroxy powder. By enabling the rapid formation of calcium phosphate from calcium and phosphate ions, which can precipitate onto the tooth surface, the addition of apatite in the toothpaste enhances its ability to restore minerals in the enamel layer. This enhancement elevates the overall quality of the toothpaste,” Prof. Dr. Pornchai Jansisyanont, Dean of the Faculty of Dentistry, concluded.

For the full and unedited release of this article, please visit: https://www.chula.ac.th/en/news/122988/

Chulalongkorn researchers win Gold, special awards at INTARG 2023 in Poland

Prof. Pol.Capt. Pharm. Dr. Suchada Sukrong, lecturer at the Faculty of Pharmaceutical Sciences and a researcher at the Center of Excellence in DNA Barcoding of Thai Medicinal Plants, Chulalongkorn University, Dr. Kannika Thongkhao, and Pharm. Chayaphol Tangpatthong have won the gold medal and two Special Awards, namely the FIRI Award in the Best Invention category from “The first institute of inventors and researchers of Iran” (FIRI), Iran, and a Special Awards from “The Industrial Property Office of the Czech Republic the Czech Metallurgical Society,” The Czech Republic, in The 16th International Invention and Innovation Show (INTARG 2023) on May 24-25, 2023, at Katowice International Conference Center, Katowice, Republic of Poland, with their “Rapid DNA immunochromatographic assay for detection of toxic Aristolochia species, the plants responsible for aristolochic acid nephropathy”

Participants from over 30 countries around the world submitted more than 300 works to this invention and innovation contest. Thailand had 29 works from 19 agencies, including Chulalongkorn University, Thammasat University, Kasetsart University, Srinakharinwirot University, Burapha University, Naresuan University, Mae Jo University, Sukhothai Thammathirat Open University, King Mongkut’s University of Technology Thonburi, King Mongkut’s University of Technology North Bangkok, King Mongkut’s Institute of Technology Ladkrabang, Rajamangala University of Technology Suvarnabhumi, Chiang Mai Rajabhat University, Princess Chulabhorn Science High School Lopburi, Satri Witthaya, and the Prince Royal’s College. Participation in this contest was supported by the National Research Council of Thailand (NRCT), Ministry of Higher Education, Science, Research and Innovation.

This innovation originated from an interest in khrai khruea, the root of the Aristolochia genus, which is used widely around the world, as well as in Thai medicinal formulas. The herb has anti-fever properties and boosts appetite. However, it contains Aristolochic acid as a chemical component, which is a carcinogen and can cause many types of kidney diseases, such as kidney failure, kidney cancer, and urinary tract cancer. The continuous monitoring of the use of khrai khruea by the research team of the Center of Excellence in DNA Barcoding of Thai Medicinal Plants, Chulalongkorn University, headed by Prof. Pol.Capt. Pharm. Dr. Suchada Sukrong, found that plants of this genus are still available for sale and mixed in medicinal recipes.

The “Rapid DNA immunochromatographic assay for detection of toxic Aristolochia species” consists of an antigen-labeled primer set and a lateral flow test kit, which can be used to accurately test the existence of Aristolochia species, e.g., khrai khruea, in various types of herbal medicines, such as pharmaceutical recipes, pharmaceutical powder, formulas, and bolus. The kit is highly sensitive and easy to use. The results can be interpreted with the naked eye in 90 minutes by reading the color lines that resemble the COVID-19 ATK or a pregnancy test kit. The “Rapid DNA immunochromatographic assay for detection of toxic Aristolochia species” can be used by entrepreneurs to inspect herbal raw materials or to inspect finished products by public health authorities and law enforcement agencies.

However, the Center intends to further develop the innovation for faster detection, which can yield results on the spot, and enable the public to test their own herbal medicines.

Chula’s pledge to be Net Zero by 2050

Chula President pledged to move ahead with greenhouse gas reduction on the Chulalongkorn University campus targeting Net Zero Greenhouse Gas Emission by 2050 and unveiled 5 pilot strategies for minimizing carbon dioxide emissions and also achieving campus sustainability.

Currently, Net Zero Emission is an issue that many countries around the world are focusing on and urgently addressing following the mandate of the United Nations Framework Convention on Climate Change (UNFCCC) 26th Conference on Climate Change (COP26) in 2021. The mandate supports the goal of limiting the global average surface temperature from rising more than 1.5°C to prevent catastrophes caused by extreme weather events.

​“Chulalongkorn University has begun collecting all greenhouse gas emissions data within the university in the academic year 2015 and found that a total of greenhouse gas emissions was 54,955.89 tons of carbon dioxide equivalent (CO2eq), the majority of which resulted from electricity use on campus. This equals 1.21 tons CO2eq emitted per student and personnel that year. Based on this finding, Chula has developed a plan and issued policies and measures to reduce greenhouse gases more earnestly and intensively,” said Professor Dr. Orathai Chavalparit, Head of the Chula Race to Zero Working Group on Policy and Planning, and lecturer from the Department of Environmental Engineering, Faculty of Engineering, Chulalongkorn University.

As a citizen of the country and the world, Chula recognizes its responsibility to the public and to take this issue seriously and to be in line with the Sustainable Development Goals (SDGs), one of Chula’s strategies for 2021-2024. The President of Chulalongkorn University, therefore, announced the pledge to reduce greenhouse gases on campus last September with two main goals as follows:

1. “Carbon Neutrality by 2040”

2. “Net Zero Greenhouse Gas Emission by 2050”

To reach its Net Zero goal, Chula needs cooperation from everyone in the Chula community and plans are needed to reduce energy consumption in both the short and long terms. Chula has designed a five-strategy Chula ’2050 Net-Zero Transition’ plan as follows:

1. Energy Transition​
Chulalongkorn University has replaced its existing energy system with a Solar-PV development — a Zero-Carbon Energy System.

“Chulalongkorn University campus is in an urban area, so space is limited, and solar energy is most suitable for the university.”

Chula has signed an agreement with the Metropolitan Electricity Authority (MEA) for a pilot project to install rooftop solar panels for 65 buildings across the campus. Currently, installation has been completed in 14 buildings, and installation in the remaining buildings is expected to be completed by the end of 2023.

“If (the panels) are installed and used in all buildings, Chula will replace 25% of the university’s electricity consumption.”

In addition, Chula will concentrate on appropriate green building designs for new constructions, such as the layout and direction of the buildings to correlate with sunlight, while emphasizing the use of natural light to reduce the use of electricity.​

2. Improving Energy System Resilience
Chula has conducted a lifetime inspection and evaluated the efficiency of electrical equipment to convert them to energy-efficient ones in common buildings such as light bulbs and air conditioners. In addition, there are improvements in indoor air conditioning systems by installing heat monitors, ventilation, and cooling systems, as well as the Building Energy Management (CU BEMs) in buildings throughout campus to effectively and efficiently monitor and control energy consumption in each building through applications and dashboards. These systems which can report peak load periods and release of carbon dioxide (CO2) is designed by the Smart Grid Research Unit (SGRU), Department of Electrical Engineering, Faculty of Engineering in collaboration with Tokyo University and the domestic and international industrial sector with funding support from the Energy Conservation Promotion Fund (ENCON Fund), Ministry of Energy.

3. Creating Green Growth
Chula has supported national and international research and cooperation including green investment to develop carbon-free technology. The Bio-Circular-Green Economy Technology & Engineering Center, Faculty of Engineering, Chulalongkorn University, has collaborated with the government sector, private sector, industrial sector, and public organizations under the name Thailand CCUS Consortium aiming at planning, research, and development of carbon capture, utilization, and storage (CCUS) technology. This is an important step in the repurposing of CO2 that was originally seen as pollution, for value-added commercial uses and elimination of pollution for the environment.

In addition, Chula researchers have successfully converted carbon dioxide into methanol using less energy and giving high yield as part of a research project Carbon Dioxide (CO2) Conversion to Higher-Valued Products with the support of the Research Cess Fund (RCF) of the Malaysia-Thai Joint Authority (MTJA).

In 2022, 2565, Chula has been focusing more on energy transition and clean energy. Chula Faculty of Engineering has signed an agreement with Hitachi Energy to promote and support the education, research, development, and technological learning on energy-related topics such as carbon neutrality, microgrid, micro electricity generation, and management system for communities using mainly renewable energy, Battery Energy Storage System (BESS), electric mobility (e-Mobility), green hydrogen, as well as studying sustainable energy future.

4. Lifestyle Transition
Chula has also campaigned for students and personnel to use public buses within the campus with choices of low-carbon transportation such as electric buses, bicycles, electric tuk-tuks, and electric scooters. Covered walkways have also been installed to connect various buildings within the University to facilitate the commute of the Chula community.

Chula has also implemented the Chula Zero Waste Project on campus and surrounding communities to strive for zero waste from the source to the destination and reduce the amount of waste to landfill using the 3Rs rules, including Reduce, Reuse, and Recycle. Participation from the Chula community, including students, personnel, and vendors on campus has also been encouraged through awareness building so that everyone pays attention to their environmental impacts, and the waste generated in their daily life on campus, as well as changing their behavior to a more sustainable lifestyle for a sustainable environment.

Earnest implementation during the first five years of the project helped reduce waste by about 40 percent which is more than the original target of 30 percent and demonstrated the potential for management to drive cognitive-behavioral change in waste management. The project also set a goal to reuse 75 percent of waste by 2040.

Moreover, Chula encourages personnel and students to carry personal glasses or water bottles to reduce the use of single-use plastic cups, while preparing drinking water dispensers, and campaigning for stores in the cafeterias to substitute biodegradable Zero waste containers for single-use plastic bags. In the future, Chula plans to support a low-carbon diet to reduce meat consumption and promote the consumption of low-carbon plant-based foods such as vegetables, fruits, grains, or protein from legumes, as well as reducing the consumption of processed foods, and the use of single-use plastic food packaging.​ These measures require cooperation from cafeteria vendors on campus.

5. The Social Transition Social Support System

To encourage the Chula community to be part of the greenhouse gas reduction drive within the campus, there are plans to organize activities and projects such as discussion forums, short clip contests, and exchanges of information between students and personnel through online media channels. This is to raise the awareness of the Chula community on the importance and consequences of climate change that would lead to behavioral change and new conscience to prepare for a sustainable low-carbon society.​

“Although the management system to reduce greenhouse gas emissions that Chula has adopted is a system that has been used abroad, many systems are not yet widespread in Thailand. Therefore, Chula would like to be one of the leaders of change and a model of educational institutions that pilot the development of green research and innovation that can reduce carbon dioxide emissions in a real and sustainable way. We believe that we can and will expand to other institutions or agencies in Thailand to work together towards a sustainable low-carbon society.” Professor Dr. Orathai concluded.

An alternative medicine for pain relief at Chula Pain Clinic

Chula Medicine researchers have successfully published an article on the injection of patient’s own platelets rich plasma into the shoulder ligaments resulting in pain reduction, heal torn ligaments and restore torn muscles as an alternative to surgery while reducing the side effects of prolonged use of pain medications.

“Pain” is a condition that no one wishes to experience. And when it occurs, people want to heal as soon as possible. This can be achieved through taking painkillers or alternative medical approaches such as acupuncture, massage, using heat compression, etc. But today, Chula Pain Clinic, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society has a new proven treatment for pain derived from the person’s own “platelets” to offer.

“Platelet-Rich Plasma (PRP) injection for shoulder ligament injuries or “rotator cuff tears” is one of the treatments we have been doing for over 5 years.” Explains Assistant Professor Marvin
Thepsoparn, MD, an anesthesiologist and pain management specialist at the Pain Clinic, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society. “This approach helps to reduce the side effects of painkillers and is very safe because the patient’s own platelets and plasma are used to inject back into patient’s injury site to stimulate self-repair,” Dr. Thepsoparn is discussing how to relieve pain with platelets.

This research was conducted in collaboration with the Orthopaedic Sports Unit of King Chulalongkorn Memorial Hospital to study pain care for people who have suffered injuries from work, sports, and abnormal body movements. These are the causes of muscle injuries and torn ligaments, which can lead to lifelong chronic pain.

“In this study, we compared the efficiency of treatments by performing an MRI of the shoulder of patients who had already received platelet injection for 6 months, and those who did not use this method to treat torn shoulder ligaments. We found that injecting of the concentration of platelets into the shoulder ligaments significantly reduced pain within 1 – 2 months and also helped repair the tear, resulting in better healing of the ligaments and a reduction in size of the tear.  As a result, patients did not have to suffer from chronic pain, avoided surgery, and eliminate the risk of continuously taking painkillers for an extended period.”

For the full and unedited release of this article, please visit: https://www.chula.ac.th/en/highlight/110448/

Chula launches the latest Parkinson’s gloves to reduce tremors

Doctors at King Chulalongkorn Memorial Hospital have developed lightweight and easy-to-use Parkinson’s gloves that can automatically reduce tremors, allowing Parkinson’s Disease patients to enjoy social life and reducing side effects from medication and risk from brain surgery.

Tremors, slowness, and stiffness are the noticeable symptoms of patients with Parkinson’s disease (PD), especially the hand tremors found in 70 percent of patients. PD patients become disabled and lack quality of life. Currently, there are 10 million PD patients worldwide, 150,000 of whom are in Thailand. 

Parkinson’s disease is currently treated with a cocktail of medications, which is unable to reduce all the tremors. Some patients with very strong tremors may need brain surgery — an undesirable option due to its high cost and many side effects. This conundrum has inspired a team of researchers at the Faculty of Medicine, Chulalongkorn University, led by Prof. Dr. Roongroj Bhidayasiri and Asst. Prof. Dr. Onanong Phokaewvarangkul to research and develop the prototype of “Tremor-reducing Parkinson’s gloves” in 2014, which was patented as a portable tremor-measuring and reducing device using electrical muscle stimulation in 2017.  Many research articles have been published in international medical journals to support the efficiency of the device. The team has now succeeded in developing the “5th generation tremor-reducing Parkinson’s gloves” which are lightweight, easy to wear, effective, and cheaper than the similar imported device.   

“The tremor-reducing Parkinson’s gloves are the first medical device that can help reduce tremors in the hands of PD patients through automatic electric stimulation of the hand muscles without having to increase their medication and reduce the risk of brain surgery,” discussed Asst. Prof. Dr. Onanong. Consisting of three main components: a glove with the muscle stimulator installed, a control panel, and a mobile phone with an application to control the device and store the tremors and stimulation for analysis, the Parkinson’s gloves work via Bluetooth connection.  

The innovation was awarded the National Innovation Award in Society and Environment (Private Sector) 2022 from the National Innovation Agency (Public Organization), and the Ministry of Higher Education, Science, Research, and Innovation.  

Read the full article at https://www.chula.ac.th/en/highlight/109695/ 

For more information, contact Prof. Dr. Roongroj Bhidayasiri, The Excellence Center for Parkinson’s Disease & Related Disorders, King Chulalongkorn Memorial Hospital, mobile phone +668-1107-9999, or visit www.chulapd.org